338: Preeclampsia is associated with placental mitochondrial dysfunction.

Is Subclinical Thyroid Dysfunction Associated With with Coronary Heart Disease?

Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyro...

Preeclampsia: linking placental ischemia with cardiovascular-renal dysfunction.

Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk

Environmental exposure to heavy metals is a potentially modifiable risk factor for preeclampsia (PE). Toxicologically, there are known interactions between the toxic metal cadmium (Cd) and essential metals such as selenium (Se) and zinc (Zn), as these metals can protect against the toxicity of Cd. As they relate to preeclampsia, the interaction between Cd and these essential metals is unknown. ...

Placental Mesenchymal Dysplasia Associated with Severe Preeclampsia: a Case Report

Placental mesenchymal dysplasia (PMD) is a relatively recently recognized, rare placental vascular anomaly characterized by placentomegaly and grapelike vesicles that may coexist with a normal fetus. Ultrasonography performed at 16 weeks of gestation revealed multiple cysts in the placenta along with a morphologically normal fetus. At 24 weeks of gestational age, severe preeclampsia symptoms we...

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia

INTRODUCTION Preeclampsia is a maternal hypertensive disorder with uncertain etiology and a leading cause of maternal and fetal mortality worldwide, causing nearly 40% of premature births delivered before 35 weeks of gestation. The first stage of preeclampsia is characterized by reduction of utero-placental blood flow which is reflected in high blood pressure and proteinuria during the second h...